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Fabgennix
ADCY2 Polyclonal Antibody, FITC
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Product Details
PAC2-FITC
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to unique amino acid sequence from rat Particulate Adenylyl Cyclase 2 protein.
Conjugate
Excitation/Emission Max
498/517 nm
View spectra
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
ADCY2 is a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate(cAMP). This enzyme is insensitive to Ca(2+)/calmodulin, and is stimulated by the G protein beta and gamma subunit complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3',5'-cyclic AMP synthetase; AC2; adenylate cyclase 2 (brain); adenylate cyclase II; Adenylate cyclase type 2; Adenylate cyclase type II; Adenylyl cyclase 2; ATP pyrophosphate-lyase 2; type II adenylate cyclase
Gene Aliases: AC2; ADCY2; HBAC2; KIAA1060; mKIAA1060
UniProt ID: (Human) Q08462, (Rat) P26769
Entrez Gene ID: (Human) 108, (Mouse) 210044, (Rat) 81636
magnesium ion binding
adenylate cyclase activity
ATP binding
adenylate cyclase binding
manganese ion binding
protein heterodimerization activity
nucleotide binding
calcium- and calmodulin-responsive adenylate cyclase activity
lyase activity
phosphorus-oxygen lyase activity
G-protein beta/gamma-subunit complex binding
metal ion binding
protein binding
cAMP biosynthetic process
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
activation of adenylate cyclase activity
cyclic nucleotide biosynthetic process
intracellular signal transduction
renal water homeostasis
adenylate cyclase-activating G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
cAMP-mediated signaling
activation of protein kinase A activity
cellular response to glucagon stimulus
cellular response to forskolin
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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