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ADCY3 Polyclonal Antibody

ADCY3 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 10

ADCY3 Antibody (19492-1-AP) in ICC/IF

Immunofluorescent analysis of ( 4% PFA ) fixed MDCK cells using 19492-1-AP (ADCY3 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

ADCY3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

ADCY3 Antibody in Immunohistochemistry (IHC)

ADCY3 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

19492-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 3 publications 3 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:50-1:500

View 7 publications 7 publications

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.65 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Target Information

This gene encodes adenylyl cyclase 3 which is a membrane-associated enzyme and catalyzes the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This protein appears to be widely expressed in various human tissues and may be involved in a number of physiological and pathophysiological metabolic processes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Preferential Expression of Ca²⁺-Stimulable Adenylyl Cyclase III in the Supraventricular Area, including Arrhythmogenic Pulmonary Vein of the Rat Heart.

Biomolecules

Okamoto Y,Aung NY,Tanaka M,Takeda Y,Takagi D,Igarashi W,Ishii K,Yamakawa M,Ono K

Fri May 20 00:00:00 UTC 2022

Phenotypic characterization of Cdkl5-knockdown neurons establishes elongated cilia as a functional assay for CDKL5 Deficiency Disorder.

Neuroscience research

Di Nardo A,Rühmkorf A,Award P,Brennecke A,Fagiolini M,Sahin M

Tue Mar 01 00:00:00 UTC 2022

Targeting the HDAC6-Cilium Axis Ameliorates the Pathological Changes Associated with Retinopathy of Prematurity.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Ran J,Zhang Y,Zhang S,Li H,Zhang L,Li Q,Qin J,Li D,Sun L,Xie S,Zhang X,Liu L,Liu M,Zhou J

Fri Jul 01 00:00:00 UTC 2022

Expression Regulation of Water Reabsorption Genes and Transcription Factors in the Kidneys of Lepus yarkandensis.

Frontiers in physiology

Luo S,Li Y,Li S,Jiang R,Deng F,Liu G,Zhang J

Sat Jul 16 00:00:00 UTC 2022

Expression Regulation of Water Reabsorption Genes and Transcription Factors in the Kidneys of Lepus yarkandensis.

Frontiers in physiology

Luo S,Li Y,Li S,Jiang R,Deng F,Liu G,Zhang J

Sat Jul 16 00:00:00 UTC 2022

Hypoglycemic flavonoids from Selaginella tamariscina (P.Beauv.) Spring.

Phytochemistry

Long HP,Liu J,Xu PS,Xu KP,Li J,Tan GS

Tue Mar 01 00:00:00 UTC 2022

Phosphosite T674A mutation in kinesin family member 3A fails to reproduce tissue and ciliary defects characteristic of CILK1 loss of function.

Developmental dynamics : an official publication of the American Association of Anatomists

Gailey CD,Wang EJ,Jin L,Ahmadi S,Brautigan DL,Li X,Xu W,Scott MM,Fu Z

Mon Feb 01 00:00:00 UTC 2021

Phenotypic Screen with TSC-Deficient Neurons Reveals Heat-Shock Machinery as a Druggable Pathway for mTORC1 and Reduced Cilia.

Cell reports

Di Nardo A,Lenoël I,Winden KD,Rühmkorf A,Modi ME,Barrett L,Ercan-Herbst E,Venugopal P,Behne R,Lopes CAM,Kleiman RJ,Bettencourt-Dias M,Sahin M

Tue Jun 23 00:00:00 UTC 2020

A Cell-Based Assay Optimized for High-Content Cilia Imaging with Primary Rat Hippocampal Neurons.

STAR protocols

Di Nardo A,Vasquez S,Sahin M

Fri Dec 18 00:00:00 UTC 2020

Aromatherapy: Activating olfactory calcium-sensing receptors impairs renal hemodynamics via sympathetic nerve-mediated vasoconstriction.

Acta physiologica (Oxford, England)

Lee SP,Wu WY,Hsiao JK,Zhou JH,Chang HH,Chien CT

Tue Jan 01 00:00:00 UTC 2019

Aromatherapy: Activating olfactory calcium-sensing receptors impairs renal hemodynamics via sympathetic nerve-mediated vasoconstriction.

Acta physiologica (Oxford, England)

Lee SP,Wu WY,Hsiao JK,Zhou JH,Chang HH,Chien CT

Tue Jan 01 00:00:00 UTC 2019

Shortened primary cilium length and dysregulated Sonic hedgehog signaling in Niemann-Pick C1 disease.

Human molecular genetics

Canterini S,Dragotto J,Dardis A,Zampieri S,De Stefano ME,Mangia F,Erickson RP,Fiorenza MT

Thu Jun 15 00:00:00 UTC 2017

Shortened primary cilium length and dysregulated Sonic hedgehog signaling in Niemann-Pick C1 disease.

Human molecular genetics

Canterini S,Dragotto J,Dardis A,Zampieri S,De Stefano ME,Mangia F,Erickson RP,Fiorenza MT

Thu Jun 15 00:00:00 UTC 2017

Bioinformatics

Protein Aliases: AC-III; AC3; Adenylate cyclase type 3; Adenylate cyclase type III; Adenylate cyclase, olfactive type; Adenylyl cyclase 3; adenylyl cyclase, type III; ATP pyrophosphate-lyase 3; type III adenylyl cyclase

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Gene Aliases: AC-III; AC3; ADCY3; KIAA0511; mKIAA0511

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UniProt ID: (Human) O60266, (Rat) P21932, (Mouse) Q8VHH7

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Entrez Gene ID: (Human) 109, (Rat) 64508, (Mouse) 104111

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Function(s)

adenylate cyclase activity calmodulin binding ATP binding calcium- and calmodulin-responsive adenylate cyclase activity metal ion binding nucleotide binding phosphorus-oxygen lyase activity protein binding lyase activity

Process(es)

cAMP biosynthetic process female meiotic division sensory perception of smell cyclic nucleotide biosynthetic process intracellular signal transduction renal water homeostasis signal transduction adenylate cyclase-activating G-protein coupled receptor signaling pathway activation of adenylate cyclase activity adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway single fertilization acrosome reaction olfactory learning cAMP-mediated signaling sperm motility activation of protein kinase A activity cellular response to glucagon stimulus cellular response to forskolin response to stimulus

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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ADCY3 Polyclonal Antibody

ADCY3 Antibody (19492-1-AP) in ICC/IF

Product Details

19492-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Target Information

Bioinformatics

Performance Guarantee

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