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Product Details
16474-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ADH4 Fusion Protein Ag9568 (1-380 aa encoded by BC022319)
Conjugate
Unconjugated
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Product Specific Information
Immunogen sequence: MGTKGKVIK CKAAIAWEAG KPLCIEEVEV APPKAHEVRI QIIATSLCHT DATVIDSKFE GLAFPVIVGH EAAGIVESIG PGVTNVKPGD KVIPLYAPLC RKCKFCLSPL TNLCGKISNL KSPASDQQLM EDKTSRFTCK GKPVYHFFGT STFSQYTVVS DINLAKIDDD ANLERVCLLG CGFSTGYGAA INNAKVTPGS TCAVFGLGGV GLSAVMGCKA AGASRIIGID INSEKFVKAK ALGATDCLNP RDLHKPIQEV IIELTKGGVD FALDCAGGSE TMKAALDCTT AGWGSCTFIG VAAGSKGLTV FPEELIIGRT INGTFFGGWK SVDSIPKLVT DYKNKKFNLD ALVTHTLPFD KISEAFDLMN QGKSIRTILI F (1-380 aa encoded by BC022319)
Target Information
This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ADH2; Alcohol dehydrogenase 4; Alcohol dehydrogenase class II; Alcohol dehydrogenase class II pi chain; Alcohol dehydrogenase II; aldehyde reductase; All-trans-retinol dehydrogenase [NAD(+)] ADH4; class II alcohol dehydrogenase, pi subunit; class II type ADH; epididymis secretory protein Li 4
Gene Aliases: Ac1002; ADH-1; ADH-2; Adh2; ADH4; HEL-S-4
UniProt ID: (Human) P08319, (Mouse) Q9QYY9
Entrez Gene ID: (Human) 127, (Mouse) 26876, (Rat) 29646
Molecular Function:
dehydrogenase
oxidoreductase
metabolite interconversion enzyme
NADPH:quinone reductase activity
alcohol dehydrogenase (NAD) activity
alcohol dehydrogenase activity, zinc-dependent
alditol:NADP+ 1-oxidoreductase activity
retinol dehydrogenase activity
all-trans retinal binding
zinc ion binding
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
benzaldehyde dehydrogenase activity
retinol binding
ethanol binding
NAD binding
oxidoreductase activity
metal ion binding
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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