Peptide sequence: PLTNLCGKIS NLKSPASDQQ LMEDKTSRFT CKGKPVYHFF GTSTFSQYTV
Sequence homology: Human: 100%
This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes.
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Protein Aliases: ADH-2; Alcohol dehydrogenase 4; Alcohol dehydrogenase 4 (class II); Alcohol dehydrogenase class II pi chain; aldehyde reductase; All-trans-retinol dehydrogenase [NAD(+)] ADH4; epididymis secretory protein Li 4; pi polypeptide
Gene Aliases: ADH-2; ADH4; HEL-S-4
UniProt ID: (Human) P08319
Entrez Gene ID: (Human) 127