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Invitrogen

ADH5 Polyclonal Antibody

View all (29) ADH5 antibodies

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ADH5 Polyclonal Antibody

Product Details

PA5-97436

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:5,000
-

ELISA (ELISA)

Assay-Dependent
-
Product Specifications

Species Reactivity

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Mouse Alcohol dehydrogenase class-3 protein (2-374AA)
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

3.74 mg/mL

Amount

100 µg

Purification

Protein G

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.03% ProClin 300

Storage conditions

-20°C or -80°C if preferred

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2812053

Target Information

This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: ADH-B2; Alcohol dehydrogenase 2; Alcohol dehydrogenase 5; Alcohol dehydrogenase B2; Alcohol dehydrogenase class-3; Alcohol dehydrogenase class-III; FALDH; FDH; Glutathione-dependent formaldehyde dehydrogenase; GSH-FDH; S-(hydroxymethyl)glutathione dehydrogenase; S-nitrosoglutathione reductase

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Gene Aliases: Adh-2; Adh-5; Adh2; Adh3; Adh5; GSNOR

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UniProt ID: (Mouse) P28474

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Entrez Gene ID: (Mouse) 11532

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Function(s)
C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity alcohol dehydrogenase (NAD) activity aldo-keto reductase (NADP) activity isocitrate dehydrogenase activity mevaldate reductase activity fatty acid binding zinc ion binding gluconate dehydrogenase activity steroid dehydrogenase activity oxidoreductase activity epoxide dehydrogenase activity 5-exo-hydroxycamphor dehydrogenase activity 2-hydroxytetrahydrofuran dehydrogenase activity formaldehyde dehydrogenase activity acetoin dehydrogenase activity phenylcoumaran benzylic ether reductase activity D-xylose:NADP reductase activity L-arabinose:NADP reductase activity D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor steroid dehydrogenase activity, acting on the CH-CH group of donors (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity 3-hydroxymenthone dehydrogenase activity very long-chain-3-hydroxyacyl-CoA dehydrogenase activity dihydrotestosterone 17-beta-dehydrogenase activity protein homodimerization activity (R)-2-hydroxyisocaproate dehydrogenase activity L-arabinose 1-dehydrogenase (NADP+) activity L-xylulose reductase (NAD+) activity metal ion binding 3-ketoglucose-reductase activity S-(hydroxymethyl)glutathione dehydrogenase activity (R)-2-hydroxyglutarate dehydrogenase activity D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity dehydrogenase oxidoreductase metabolite interconversion enzyme
Process(es)
retinoid metabolic process respiratory system process ethanol catabolic process ethanol oxidation peptidyl-cysteine S-nitrosylation response to lipopolysaccharide positive regulation of blood pressure formaldehyde catabolic process response to nitrosative stress response to redox state oxidation-reduction process
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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