PA5-27075 targets Adenosine A1 Receptor in WB applications and shows reactivity with Human and mouse samples.
The PA5-27075 immunogen is synthetic peptide corresponding to a region within amino acids 162 and 257 of Human Adenosine A1 Receptor.
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The protein encoded by this gene is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5' UTR have been found for this gene.
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Protein Aliases: adenosine A1 receptor variant 1; adenosine A1 receptor variant 2; Adenosine receptor A1; RDC7
Gene Aliases: A1-AR; A1AR; A1R; AA1R; ADORA1; AI848715; BB176431; RDC7; Ri