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ADORA2B Polyclonal Antibody
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Product Details
BS-10205R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human ADORA2B, amino acids 251-300.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
ADORA2B encodes an adenosine receptor that is a member of the G protein-coupled receptor superfamily. This integral membrane protein stimulates adenylate cyclase activity in the presence of adenosine. This protein also interacts with netrin-1, which is involved in axon elongation. The gene is located near the Smith-Magenis syndrome region on chromosome 17.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: A2b receptor; A2b, Rs; Adenosine receptor A2b; HGNC:264; netrin-1 receptor
Gene Aliases: A2b; A2BAR; A2BR; AA2BR; ADORA2; ADORA2B; AI480866; AI605384
UniProt ID: (Human) P29275, (Rat) P29276, (Mouse) Q60614
Entrez Gene ID: (Human) 136, (Rat) 29316, (Mouse) 11541
adenosine receptor signaling pathway
positive regulation of chronic inflammatory response to non-antigenic stimulus
signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
activation of adenylate cyclase activity
positive regulation of vascular endothelial growth factor production
positive regulation of cGMP-mediated signaling
cGMP-mediated signaling
positive regulation of chemokine production
positive regulation of interleukin-6 production
vasodilation
mast cell degranulation
positive regulation of mast cell degranulation
relaxation of vascular smooth muscle
presynaptic modulation of chemical synaptic transmission
positive regulation of cell proliferation
negative regulation of cell proliferation
positive regulation of norepinephrine secretion
positive regulation of steroid biosynthetic process
positive regulation of cAMP biosynthetic process
positive regulation of cGMP biosynthetic process
positive regulation of guanylate cyclase activity
cellular response to extracellular stimulus
negative regulation of collagen biosynthetic process
positive regulation of catecholamine secretion
regulation of angiogenesis
positive regulation of vasodilation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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