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Invitrogen
ADORA2B Polyclonal Antibody
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FIGURE: 1 / 2
ADORA2B Antibody (PA5-77849) in IHC (P)
ADORA2B Polyclonal Antibody detects Adenosine A2b Receptor protein at cytoplasm in mouse brain by immunohistochemical analysis. Sample: Paraffin-embedded mouse brain. ADORA2B Polyclonal Antibody (Product # PA5-77849) diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-77849
Product Specifications
Species Reactivity
Cat,
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide encompassing a sequence within the Extracellular domain of human Adenosine A2b Receptor. The exact sequence is proprietary.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.53 mg/mL
Amount
53 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Control: U87-MG, SK-N-SH, IMR32, SK-N-AS, mouse brain, rat brain
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
ADORA2B encodes an adenosine receptor that is a member of the G protein-coupled receptor superfamily. This integral membrane protein stimulates adenylate cyclase activity in the presence of adenosine. This protein also interacts with netrin-1, which is involved in axon elongation. The gene is located near the Smith-Magenis syndrome region on chromosome 17.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: A2b receptor; A2b, Rs; HGNC:264; netrin-1 receptor; unnamed protein product
Gene Aliases: A2b; A2BAR; A2BR; AA2BR; ADORA2; ARA2B
UniProt ID: (Human) P29275, (Mouse) Q60614, (Rat) P29276
Entrez Gene ID: (Human) 136, (Mouse) 11541, (Rat) 29316
positive regulation of endothelial cell proliferation
adenosine receptor signaling pathway
positive regulation of chronic inflammatory response to non-antigenic stimulus
G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
positive regulation of cell proliferation
negative regulation of cell proliferation
positive regulation of vascular endothelial growth factor production
positive regulation of endothelial cell migration
regulation of cell communication
positive regulation of norepinephrine secretion
positive regulation of steroid biosynthetic process
regulation of glucose metabolic process
regulation of signaling
positive regulation of guanylate cyclase activity
positive regulation of chemokine production
positive regulation of interleukin-6 production
negative regulation of collagen biosynthetic process
positive regulation of catecholamine secretion
vasodilation
positive regulation of mast cell degranulation
relaxation of vascular smooth muscle
presynaptic modulation of chemical synaptic transmission
positive regulation of cAMP/PKA signal transduction
response to angiotensin
regulation of amine transport
regulation of secretion by cell
activation of adenylate cyclase activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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