Proteintech
Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:2,000 | View 2 publications 2 publications |
Immunohistochemistry (IHC) |
- | View 1 publication 1 publication |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:200 | - |
Immunocytochemistry (ICC/IF) |
- | View 1 publication 1 publication |
Flow Cytometry (Flow) |
0.2 µg/1x10^6 cells | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Human, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
ADRB2 Fusion Protein Ag3715 (220-413 aa encoded by BC012481) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.38 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.1% sodium azide |
Storage conditions |
-20°C |
This antibody detects ADRB2 with an apparent molecular weight of 50-55 kDa as has been shown by some researches.
Immunogen sequence: SRVFQEAKR QLQKIDKSEG RFHVQNLSQV EQDGRTGHGL RRSSKFCLKE HKALKTLGII MGTFTLCWLP FFIVNIVHVI QDNLIRKEVY ILLNWIGYVN SGFNPLIYCR SPDFRIAFQE LLCLRRSSLK AYGNGYSSNG NTGEQSGYHV EQEKENKLLC EDLPGTEDFV GHQGTVPSDN IDSPGRNCST NDSLL (220-413 aa encoded by BC012481)
Adrenergic receptors (ARs) are members of the 7-transmembrane domain G-protein-coupled receptor superfamily that bind the endogenous catecholamines epinephrine and norepinephrine. Pharmacological, structural, and molecular cloning data indicate significant heterogeneity within this receptor family. Nine receptor subtypes have been identified thus far including three alpha-1 AR subtypes (1A/D, 1B, and 1C), three alpha-2 ARs (2A, 2B, and 2C), and three beta AR subtypes (1, 2, and 3). ARs participate in either the onset or maintenance of several disease states including hypertension, cardiac dysfunction (congestive heart failure, ischemia, arrhythmias), diabetes, glaucoma, depression, and impotence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Adrenergic beta 2- receptor surface; adrenergic receptor, beta 2; adrenergic, beta-2-, receptor, surface; adrenoceptor beta 2 surface; adrenoceptor beta 2, surface; AR beta2; beta 2-AR; Beta-2 adrenergic receptor; Beta-2 adrenoceptor; Beta-2 adrenoreceptor; beta2-Adrenoreceptor; catecholamine receptor; HGNC:286
Gene Aliases: Adrb-2; ADRB2; ADRB2R; ADRBR; B2AR; Badm; BAR; BETA2AR; Gpcr7
UniProt ID: (Human) P07550, (Mouse) Q8BH38
Entrez Gene ID: (Human) 154, (Mouse) 11555, (Rat) 24176
Molecular Function:
G-protein coupled receptor
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support