Search
Rockland
AGAP2 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
200-401-946
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
This protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein corresponding to amino acids 1-836 of human AGAP2 protein.
Conjugate
Form
Lyophilized
Concentration
2 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.02M potassium phosphate, pH 7.2, with 0.15M NaCl
Contains
0.01% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Store vial at 4° C prior to restoration. For extended storage aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
This protein A purified antibody is directed against human AGAP2 protein. A BLAST analysis was used to suggest cross reactivity with AGAP2 protein from mouse and rat based on 93% and 95% protein:protein homologies, respectively, with the immunizing sequence. Reactivity against homologues from other sources is not known.
Target Information
The protein encoded by this gene belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase. It is overexpressed in cancer cells, and promotes cancer cell invasion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: AGAP-2; Arf GAP with GTP-binding protein-like, ANK repeat and PH domains 2; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2; centaurin gamma1; centaurin, gamma 1; Centaurin-gamma-1; Cnt-g1; FLJ16430; GGAP2; GTP-binding and GTPase activating protein 2; GTP-binding and GTPase-activating protein 2; Phosphatidylinositol 3-kinase enhancer; phosphoinositide 3-kinase enhancer; PIKE; PIKE-L; unnamed protein product
Gene Aliases: AGAP-2; AGAP2; CENTG1; cnt-g1; GGAP2; KIAA0167; mKIAA0167; PIKE
UniProt ID: (Human) Q99490, (Mouse) Q3UHD9
Entrez Gene ID: (Human) 116986, (Mouse) 216439
small GTPase mediated signal transduction
positive regulation of phosphatidylinositol 3-kinase signaling
endosomal transport
actin cytoskeleton organization
positive regulation of mammary gland epithelial cell proliferation
negative regulation of protein catabolic process
negative regulation of apoptotic process
negative regulation of neuron apoptotic process
positive regulation of GTPase activity
regulation of phosphatidylinositol 3-kinase activity
positive regulation of protein kinase activity
positive regulation of transcription from RNA polymerase II promoter
positive regulation of JAK-STAT cascade
mammary gland alveolus development
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
protein transport
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support