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Immunogen sequence: MVMAAKKGP GPGGGVSGGK AEAEAASEVW CRRVRELGGC SQAGNRHCFE CAQRGVTYVD ITVGSFVCTT CSGLLRGLNP PHRVKSISMT TFTEPEVVFL QSRGNEVCRK IWLGLFDART SLVPDSRDPQ KVKEFLQEKY EKKRWYVPPD QVKGPTYTKG SASTPVQGSI PEGKPLRTLL GDPAPSLSVA ASTSSQPVSQ SHARTSQARS TQPPPHSSVK KASTDLLADI GGDPFAAPQM APAFAAFPAF GGQTPSQGGF ANFDAFSSGP SSSVFGSLPP AGQASFQAQP TPAGSSQGTP F (1-300 aa encoded by BC017329)
This gene is a member of the HIV-1 Rev binding protein (HRB) family and encodes a protein with one Arf-GAP zinc finger domain, several phe-gly (FG) motifs, and four asn-pro-phe (NPF) motifs. This protein interacts with Eps15 homology (EH) domains and plays a role in the Rev export pathway, which mediates the nucleocytoplasmic transfer of proteins and RNAs. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Arf-GAP domain and FG repeat-containing protein 2; arf-GAP domain and FG repeats-containing protein 2; HIV-1 Rev-binding protein-like protein; nucleoporin; RAB-R; Rev/Rex activation domain binding protein-related; Rev/Rex activation domain-binding protein related
Gene Aliases: A630095P14Rik; AGFG2; HRBL; RAB-R; RABR
UniProt ID: (Human) O95081, (Mouse) Q80WC7
Entrez Gene ID: (Human) 3268, (Rat) 304375, (Mouse) 231801
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