This gene encodes an enzyme that converts lysophosphatidic acid (LPA) into phosphatidic acid (PA). LPA and PA are two phospholipids involved in signal transduction and in lipid biosynthesis in cells. This enzyme localizes to the endoplasmic reticulum. This gene is located in the class III region of the human major histocompatibility complex. Alternative splicing results in two transcript variants encoding the same protein.
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Protein Aliases: 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha; 1-acylglycerol-3-phosphate O-acyltransferase 1; 1-acylglycerol-3-phosphate O-acyltransferase 1 (acetoacetly Coenzyme A thiolase); 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha); 1-AGP acyltransferase 1; 1-AGPAT 1; LPAAT-alpha; Lysophosphatidic acid acyltransferase alpha; lysophospholipid acyltransferase; Protein G15
Gene Aliases: 1-AGPAT1; AGPAT1; G15; LPAAT-alpha; LPAATA
UniProt ID: (Human) Q99943
Entrez Gene ID: (Human) 10554