Invitrogen

AGPS Polyclonal Antibody

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AGPS Antibody in Immunofluorescence (IF) — Immunofluorescent staining of AGPS in human cell line U-2 OS using an AGPS Polyclonal Antibody (Product # PA5-56398) shows localization to peroxisomes.

AGPS Antibody in Immunohistochemistry (IHC) — Immunohistochemical staining of AGPS in human lateral ventricle shows strong cytoplasmic positivity in neuronal cells. Samples were probed using an AGPS Polyclonal Antibody (Product # PA5-56398).

Product Details

Tested Applications

Dilution

Immunocytochemistry (ICC)

1-4 µg/mL

Immunofluorescence (IF)

1-4 µg/mL

Immunohistochemistry (IHC)

1:200-1:500

Product Specifications

Species Reactivity

Human

Host / Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human AGPS

Conjugate

Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

RRID

AB_2637770

Product Specific Information

Immunogen sequence: QIELTGKRYP LSGMGLPTFK EWIQNTLGVN VEHKTTSKAS LNPSDTPPSV VNEDFLHDLK ETNISYSQEA DDRVFRAHGH CLH

Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 81%.

Target Information

This gene is a member of the FAD-binding oxidoreductase/transferase type 4 family. It encodes a protein that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetonephosphate (DHAP) is converted to alkyl-DHAP by the addition of a long chain alcohol and the removal of a long-chain acid anion. The protein is localized to the inner aspect of the peroxisomal membrane and requires FAD as a cofactor. Mutations in this gene have been associated with rhizomelic chondrodysplasia punctata, type 3 and Zellweger syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: ADAP-S; ADAS; ADHAPS; ADPS; Aging-associated gene 5 protein; aging-associated protein 5; ALDHPSY; Alkyl-DHAP synthase; alkyldihydroxyacetonephosphate synthase; Alkyldihydroxyacetonephosphate synthase, peroxisomal; Alkylglycerone-phosphate synthase; peroxisomal

Gene Aliases: AAG5; ADAP-S; ADAS; ADHAPS; ADPS; AGPS; ALDHPSY; RCDP3

UniProt ID: (Human) O00116

Entrez Gene ID: (Human) 8540

Molecular Function: dehydrogenase oxidoreductase