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|Tested species reactivity||Bovine, Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide made to an N-terminal portion of the mouse protein (within residues 1-50).|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 30% glycerol|
|Contains||0.1% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:300|
|Western Blot (WB)||1 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
hAG-2 and hAG-3 are recently discovered human homologues of the secreted Xenopus laevis proteins XAG-1/2 (AGR-1/2) that are expressed in the cement gland, an ectodermal organ in the head associated with anteroposterior fate determination during early development(1). Although the roles of hAG-2 and hAG-3 in mammalian cells are unknown, both proteins share a high degree of protein sequence homology and lie adjacent to one another on chromosome 7p21. AGR2 is expressed in a number of different tumor types and is being investigated for its use as a potential diagnostic and therapeutic target in various cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
AG-2; AG2; anterior gradient 2 homolog; anterior gradient 2 homologue; anterior gradient homolog 2; anterior gradient protein 2 homolog; epididymis secretory protein Li 116; GOB-4; HAG-2; HPC8; member 17; PDIA17; protein disulfide isomerase family A; protein disulfide isomerase family A, member 17; protein Gob-4; secreted cement gland homolog; secreted cement gland protein XAG-2 homolog; UNQ515/PRO1030
AG2; AGR2; Agr2h; BOS_4050; GOB-4; Gob4; HAG-2; HEL-S-116; mAG-2; PDIA17; UNQ515/PRO1030; XAG-2