Recommended positive controls: A431, HepG2.
Predicted reactivity: Mouse (98%), Rat (97%), Zebrafish (86%), Xenopus laevis (90%), Pig (98%), Chimpanzee (100%), Bovine (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
S-adenosylhomocysteine hydrolase (AHCY) catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Acetylation; Adenosylhomocysteinase; AdoHcyase; Hydrolase; NAD; Polymorphism; S-adenosyl-L-homocysteine hydrolase; S-adenosylhomocysteine hydrolase
Gene Aliases: adoHcyase; AHCY; SAHH
UniProt ID: (Human) P23526
Entrez Gene ID: (Human) 191
Molecular Function: hydrolase