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Proteintech
AIDA Polyclonal Antibody
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Product Details
23724-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
AIDA Fusion Protein Ag20588 (1-306 aa encoded by BC015535)
Conjugate
Form
Liquid
Concentration
0.24 mg/mL
Amount
36 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSEVTRSLL QRWGASFRRG ADFDSWGQLV EAIDEYQILA RHLQKEAQAQ HNNSEFTEEQ KKTIGKIATC LELRSAALQS TQSQEEFKLE DLKKLEPILK NILTYNKEFP FDVQPVPLRR ILAPGEEENL EFEEDEEEGG AGAGSPDSFP ARVPGTLLPR LPSEPGMTLL TIRIEKIGLK DAGQCIDPYI TVSVKDLNGI DLTPVQDTPV ASRKEDTYVH FNVDIELQKH VEKLTKGAAI FFEFKHYKPK KRFTSTKCFA FMEMDEIKPG PIVIELYKKP TDFKRKKLQL LTKKPLYLHL HQTLHKE (1-306 aa encoded by BC015535)
Target Information
AIDA acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Axin interaction partner and dorsalization antagonist; Axin interactor, dorsalization-associated protein; unnamed protein product
Gene Aliases: 2610208M17Rik; AIDA; BC004835; C1orf80
UniProt ID: (Human) Q96BJ3, (Mouse) Q8C4Q6
Entrez Gene ID: (Human) 64853, (Mouse) 108909
multicellular organism development
dorsal/ventral pattern formation
negative regulation of Wnt signaling pathway
regulation of protein homodimerization activity
negative regulation of JUN kinase activity
negative regulation of JNK cascade
determination of ventral identity
negative regulation of determination of dorsal identity
negative regulation of protein complex assembly
regulation of protein complex assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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