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Fabgennix
AIM2 Polyclonal Antibody, FITC
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Product Details
AIM2-FITC
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide taken within amino acid region 240-340 on human AIM2 protein.
Conjugate
Excitation/Emission Max
498/517 nm
View spectra
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Absent in melanoma 2; Ifi-210; Interferon-inducible protein 210; Interferon-inducible protein AIM2; Interferon-inducible protein p210; RP11-520H16.3; unnamed protein product
Gene Aliases: AIM2; Gm1313; Ifi210; PYHIN4
UniProt ID: (Human) O14862, (Mouse) Q91VJ1
Entrez Gene ID: (Human) 9447, (Mouse) 383619
activation of innate immune response
pattern recognition receptor signaling pathway
positive regulation of defense response to virus by host
immune system process
inflammatory response
immune response
cellular response to DNA damage stimulus
brain development
negative regulation of NF-kappaB transcription factor activity
positive regulation of interleukin-1 beta production
tumor necrosis factor-mediated signaling pathway
cellular response to interferon-beta
T cell homeostasis
innate immune response
positive regulation of inflammatory response
regulation of behavior
positive regulation of NF-kappaB transcription factor activity
protein maturation
defense response to virus
negative regulation of protein kinase B signaling
neuron cellular homeostasis
pyroptosis
cellular response to cytokine stimulus
cellular response to xenobiotic stimulus
AIM2 inflammasome complex assembly
pyroptotic cell death
pyroptosome complex assembly
apoptotic process
positive regulation of protein oligomerization
cellular response to drug
interleukin-1 beta secretion
positive regulation of interleukin-1 beta secretion
positive regulation of cysteine-type endopeptidase activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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