The protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded protein can bind specifically to and inhibit the activity of hepatitis B virus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AH receptor-interacting protein; AIP; Aryl-hydrocarbon receptor-interacting protein; HBV X-associated protein 2; HBV-X associated protein; Immunophilin homolog ARA9; Immunophilin XAP2; XAP-2
Gene Aliases: AA408703; AIP; ARA9; AW476050; D19Bwg1412e; FKBP16; FKBP37; SMTPHN; XAP-2; XAP2
Molecular Function: chaperone