This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated. View Details
PA1-514 detects aryl hydrocarbon receptor interacting protein (AIP) from mouse samples.
PA1-514 has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~38 kDa protein representing AIP from Hepa 1 SV40 cell lysate, as well as recombinant mouse AIP.
PA1-514 immunogen is full length, bacterially expressed mouse recombinant AIP.
The protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded protein can bind specifically to and inhibit the activity of hepatitis B virus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AH receptor-interacting protein; AIP; Aryl-hydrocarbon receptor-interacting protein; HBV X-associated protein 2; Immunophilin homolog ARA9; XAP-2
Gene Aliases: AA408703; AIP; ARA9; AW476050; D19Bwg1412e; FKBP16; FKBP37; SMTPHN; XAP-2; XAP2
Molecular Function: chaperone