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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||18 amino acid peptide near the carboxy terminus of human AJAP1|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Western Blot (WB)||1-2 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
A recommended positive control is rat liver tissue lysate.
The Adherens Junction Associated Protein 1 (AJAP1) plays a key role in cell adhesion and cell migration. It is a transmembrane protein found on the basolateral surface of epithelium and expressed by multiple types of epithelium. AJAP1 interacts with E-Cadherin and appears to promote the internalization of E-Cadherin upon growth factor stimulation. This facilitates the dissolution of adherens junctions with an increase in cell motility.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
adherens junction associated protein 1; adherens junction-associated protein 1; Adherens junctions associated protein 1; likely ortholog of H. sapiens transmembrane protein SHREW1; membrane protein shrew-1; MOT8; Neumo48; SHREW1; transmembrane protein SHREW1
AJAP1; Gm573; MOT8; Neumo48; SHREW-1; SHREW1