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Invitrogen
AJUBA Polyclonal Antibody
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Product Details
PA5-100381
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human AJUBA(Accession Q96IF1), corresponding to amino acid residues S202-L252.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total Ajuba.
Target Information
AJUBA (Ajuba LIM Protein) is a Protein Coding gene. Diseases associated with AJUBA include Wilson-Turner X-Linked Mental Retardation Syndrome and Syndromic X-Linked Intellectual Disability. Among its related pathways are Hippo signaling pathway and Adhesion. Gene Ontology (GO) annotations related to this gene include chromatin binding and actin filament binding. An important paralog of this gene is LIMD1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ajuba homolog; Ajuba protein; jub, ajuba homolog; LIM domain containing protein; LIM domain-containing protein ajuba; protein ajuba; unnamed protein product
Gene Aliases: AJUBA; JUB
UniProt ID: (Human) Q96IF1, (Mouse) Q91XC0, (Rat) Q5U2Z2
Entrez Gene ID: (Human) 84962, (Mouse) 16475, (Rat) 85265
negative regulation of transcription from RNA polymerase II promoter
response to hypoxia
regulation of transcription, DNA-templated
cytoskeleton organization
cell adhesion
protein localization
positive regulation of biosynthetic process
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
lamellipodium assembly
regulation of cell migration
gene silencing by RNA
positive regulation of protein complex assembly
gene silencing by miRNA
miRNA mediated inhibition of translation
wound healing, spreading of epidermal cells
negative regulation of hippo signaling
positive regulation of I-kappaB kinase/NF-kappaB signaling
glycerophospholipid biosynthetic process
focal adhesion assembly
regulation of cellular response to hypoxia
transcription, DNA-templated
cell cycle
positive regulation of cellular biosynthetic process
negative regulation of kinase activity
positive regulation of kinase activity
cellular protein localization
regulation of GTPase activity
positive regulation of MAP kinase activity
negative regulation of nucleic acid-templated transcription
positive regulation of gene silencing by miRNA
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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