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AK6 Antibody (PA5-104541) in ICC/IF
Immunocytochemistry analysis of AK6 in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with AK6 polyclonal antibody (Product # PA5-104541) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
Product Details
PA5-104541
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human AK6(Accession Q9Y3D8), corresponding to amino acid residues G15-L65.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2853841
Product Specific Information
Antibody detects endogenous levels of total KAD6.
Target Information
Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. AMP and dAMP are the preferred substrates, but CMP and dCMP are also good substrates. IMP is phosphorylated to a much lesser extent. All nucleoside triphosphates ATP, GTP, UTP, CTP, dATP, dCTP, dGTP, and TTP are accepted as phosphate donors. CTP is the best phosphate donor, followed by UTP, ATP, GTP and dCTP. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Adenylate kinase isoenzyme 6; adenylate kinase isoenzyme 6 {ECO:0000255|HAMAP-Rule:MF_03173}; Adrenal gland protein AD-004; AK/ATPase; AK/ATPase {ECO:0000255|HAMAP-Rule:MF_03173}; AK6; AK6 {ECO:0000255|HAMAP-Rule:MF_03173}; ATP-AMP transphosphorylase 6; coilin interacting nuclear ATPase protein; coilin interacting protein; Coilin-interacting nuclear ATPase protein; coilin-interacting nuclear ATPase protein {ECO:0000255|HAMAP-Rule:MF_03173}; Dual activity adenylate kinase/ATPase; dual activity adenylate kinase/ATPase {ECO:0000255|HAMAP-Rule:MF_03173}; hCINAP
Gene Aliases: 2810046E22Rik; 4921516M08Rik; AD-004; AK/ATPase; AK6; CGI-137; CINAP; CIP; hCINAP
UniProt ID: (Human) Q9Y3D8, (Rat) Q5EB68, (Mouse) Q8VCP8
Entrez Gene ID: (Human) 102157402, (Rat) 102238592, (Mouse) 102216272
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