PA5-30266 targets AKAP1 in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-30266 immunogen is recombinant fragment corresponding to a region within amino acids 63 and 300 of Human AKAP1.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion. This protein is speculated to be involved in the cAMP-dependent signal transduction pathway and in directing RNA to a specific cellular compartment.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: A kinase (PRKA) anchor protein 1; A-kinase anchor protein 1; A-kinase anchor protein 1, mitochondrial; A-kinase anchor protein 149 kDa; AKAP; AKAP 149; AKAP121; AKAP149; AKAP84; D-AKAP-1; D-AKAP1; Dual specificity A-kinase-anchoring protein 1; dual-specificity A-kinase anchoring protein 1; mitochondrial; PPP1R43; PRKA1; protein kinase A anchoring protein 1; Protein kinase A-anchoring protein 1; protein kinase A1; protein phosphatase 1; protein phosphatase 1, regulatory subunit 43; regulatory subunit 43; S-AKAP84; SAKAP84; spermatid A-kinase; Spermatid A-kinase anchor protein 84; testicular secretory protein Li 5; tudor domain containing 17
Gene Aliases: AKAP; AKAP1; AKAP121; AKAP149; AKAP84; D-AKAP1; PPP1R43; PRKA1; SAKAP84; TDRD17
UniProt ID: (Human) Q92667
Entrez Gene ID: (Human) 8165