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|Tested species reactivity||Rat|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (RKVKGKEQEKTSD) corresponding to the internal amino acids of AKAP10|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||0.3-1 ug/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody is predicted to react with bovine, canine, human and mouse based on sequence homology.
The A-kinase anchor proteins are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein interacts with both the type I and type II regulatory subunits of PKA; therefore, it is a dual-specific AKAP. This protein is highly enriched in mitochondria. It contains RGS domains, in addition to a PKA-RII subunit-binding domain. The mitochondrial localization and the presence of RGS domains may have important implications for the function of this protein in PKA and G protein signal transduction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
A kinase (PRKA) anchor protein 10; A kinase anchor protein 10, mitochondrial; A-kinase anchor protein 10; A-kinase anchor protein 10, mitochondrial; AKAP10; D-AKAP2; Dual specific A kinase anchoring protein 2; dual-specificity A-kinase anchoring protein 2; MGC9414; mitochondrial A kinase PPKA anchor protein 10; protein kinase A anchoring protein 10