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Product Details
12591-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
AKAP7 Fusion Protein Ag3297 (1-81 aa encoded by BC016927)
Conjugate
Unconjugated
Form
Liquid
Concentration
0.16 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody can recognize all the isoforms of AKAP7.
Immunogen sequence: MGQLCCFPF SRDEGKISEK NGGEPDDAEL VRLSKRLVEN AVLKAVQQYL EETQNKNKPG EGSSVKTEAA DQNGNDNENN RK (1-81 aa encoded by BC016927)
Target Information
This gene encodes a member of the A-kinase anchoring protein family, a group of functionally related proteins that bind to a regulatory subunit of cAMP-dependent protein kinase A and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described. Additional variants exist, but their full-length natures have not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: A kinase (PRKA) anchor protein 7; A-kinase anchor protein 18; A-kinase anchor protein 18 kDa; A-kinase anchor protein 18 {ECO:0000250|UniProtKB:F8VQ58}; A-kinase anchor protein 7; A-kinase anchor protein 7 isoform alpha; A-kinase anchor protein 7 isoform gamma; A-kinase anchor protein 7 isoforms alpha and beta; A-kinase anchor protein 7 isoforms delta and gamma; A-kinase anchor protein 9 kDa; A-kinase anchoring protein 18 ,isoform delta; AKAP 18; AKAP 9; AKAP-18; AKAP-18 {ECO:0000250|UniProtKB:F8VQ58}; AKAP-7 isoform alpha; AKAP-7 isoform gamma; AKAP-7 isoforms alpha and beta; AKAP-7 isoforms delta and gamma; akap7; akap7 {ECO:0000312|RGD:1303071}; PRKA7 isoform alpha; PRKA7 isoform gamma; PRKA7 isoforms alpha/beta; PRKA7 isoforms delta and gamma; protein kinase A anchoring protein 7; Protein kinase A-anchoring protein 7 isoform alpha; Protein kinase A-anchoring protein 7 isoform gamma; Protein kinase A-anchoring protein 7 isoforms alpha/beta; Protein kinase A-anchoring protein 7 isoforms delta and gamma
Gene Aliases: 6430401D08; AI662165; AKAP-18; AKAP15; AKAP18; AKAP18d; AKAP7; BB170514
UniProt ID: (Human) O43687, (Mouse) O55074, (Rat) Q6JP77
Entrez Gene ID: (Human) 9465, (Mouse) 432442, (Rat) 361458
biological_process
transmembrane receptor protein serine/threonine kinase signaling pathway
protein localization
regulation of protein kinase A signaling
regulation of membrane repolarization
cellular response to cAMP
positive regulation of potassium ion transmembrane transport
positive regulation of delayed rectifier potassium channel activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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