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Proteintech
AKAP7 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
12591-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
AKAP7 Fusion Protein Ag3297 (1-81 aa encoded by BC016927)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.16 mg/mL
Amount
24 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody can recognize all the isoforms of AKAP7.
Immunogen sequence: MGQLCCFPF SRDEGKISEK NGGEPDDAEL VRLSKRLVEN AVLKAVQQYL EETQNKNKPG EGSSVKTEAA DQNGNDNENN RK (1-81 aa encoded by BC016927)
Target Information
This gene encodes a member of the A-kinase anchoring protein family, a group of functionally related proteins that bind to a regulatory subunit of cAMP-dependent protein kinase A and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described. Additional variants exist, but their full-length natures have not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: A kinase (PRKA) anchor protein 7; A-kinase anchor protein 18; A-kinase anchor protein 18 kDa; A-kinase anchor protein 9 kDa; A-kinase anchoring protein; A-kinase anchoring protein 18 ,isoform delta; AKAP 18; AKAP 9; AKAP-18; AKAP18 beta; AKAP18 gamma; PRKA; protein kinase A anchoring protein 7; unnamed protein product
Gene Aliases: 6430401D08; AKAP-18; AKAP15; AKAP18; AKAP18d
UniProt ID: (Human) O43687, (Mouse) O55074, (Rat) Q6JP77
Entrez Gene ID: (Human) 9465, (Mouse) 432442, (Rat) 361458
action potential
transmembrane receptor protein serine/threonine kinase signaling pathway
protein localization
modulation of synaptic transmission
regulation of membrane repolarization
cellular response to cAMP
cAMP/PKA signal transduction
positive regulation of potassium ion transmembrane transport
ion transport
intracellular signal transduction
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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