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Immunogen sequence: RLEDSLHQP LQGSPTRPAS AFDRPARTRG RPADSPATWG SHYGSKSTER LPGEPRGEEQ IVPPGRQRAR SSSVPREVLR LSLSSESELP SLPLFSEKSK TTKDSPQAAR DGKRGVGSAG WPDRVTFRGQ YTGHEYHVLS PKAVPKGNGT VSCPHCRPIR TQDAGGAVTG DPLGPPPADT LQCPLCGQVG SPPEADGPGS ATSGAEKATT RRKAPSTPSP KQRSKQAGSS PRPPPGLWYL ATAPPAPAPP AFAYISSVPI MPYPPAAVYY APAGPTSAQP AAKWPPTASP PPARRHRHSI QLDLGDLEEL NKALSRAVQA AESVRSTTRQ MRSSLSADLR QAHSLRGSCL F (1090-1439 aa encoded by BC055285)
AKNA is a transcription factor that specifically activates the expression of the CD40 receptor and its ligand CD40L/CD154, two cell surface molecules on lymphocytes that are critical for antigen-dependent-B-cell development. It binds to A/T-rich promoters.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AKNA transcript F2; AT-hook transcription factor AKNA; AT-hook-containing transcription factor; Microtubule organization protein AKNA
Gene Aliases: AKNA; KIAA1968
UniProt ID: (Human) Q7Z591
Entrez Gene ID: (Human) 80709
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