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Product Details
15439-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
AKR1B1 Fusion Protein Ag7142 (1-316 aa encoded by BC000260)
Conjugate
Form
Liquid
Concentration
0.27 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MASRLLLNN GAKMPILGLG TWKSPPGQVT EAVKVAIDVG YRHIDCAHVY QNENEVGVAI QEKLREQVVK REELFIVSKL WCTYHEKGLV KGACQKTLSD LKLDYLDLYL IHWPTGFKPG KEFFPLDESG NVVPSDTNIL DTWAAMEELV DEGLVKAIGI SNFNHLQVEM ILNKPGLKYK PAVNQIECHP YLTQEKLIQY CQSKGIVVTA YSPLGSPDRP WAKPEDPSLL EDPRIKAIAA KHNKTTAQVL IRFPMQRNLV VIPKSVTPER IAENFKVFDF ELSSQDMTTL LSYNRNWRVC ALLSCTSHKD YPFHEEF (1-316 aa encoded by BC000260)
Target Information
Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Aldehyde reductase; aldehyde reductase 1; Aldehyde reductase 1 (low Km aldose reductase) (5.8 kb PstI fragment, probably the functional gene); aldo-keto reductase family 1; Aldo-keto reductase family 1 member B1; aldo-keto reductase family 1, member B1 (aldose reductase); aldo-keto reductase family 1, member B4 (aldose reductase); Aldose reductase; AR; Lii5-2 CTCL tumor antigen; low Km aldose reductase; member B1 (aldose reductase)
Gene Aliases: ADR; AKR1B1; Akr1b3; Akr1b4; ALDR1; ALDRED; Alr; ALR-P-I; ALR2; AR; RATALDRED
UniProt ID: (Human) P15121, (Rat) P07943
Entrez Gene ID: (Human) 231, (Rat) 24192
tissue homeostasis
carbohydrate metabolic process
sorbitol biosynthetic process
C21-steroid hormone biosynthetic process
response to stress
response to water deprivation
naphthalene metabolic process
stress-activated protein kinase signaling cascade
norepinephrine metabolic process
daunorubicin metabolic process
doxorubicin metabolic process
fructose biosynthetic process
positive regulation of JAK-STAT cascade
positive regulation of smooth muscle cell proliferation
oxidation-reduction process
maternal process involved in female pregnancy
cellular response to hydrogen peroxide
inner medullary collecting duct development
response to thyroid hormone
cellular response to methylglyoxal
cellular response to peptide
monosaccharide metabolic process
response to organic substance
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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