This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis.
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Protein Aliases: AKR1B10; AKR1B11; AKR1B12; Aldo-keto reductase family 1 member B10; aldo-keto reductase family 1, member B10; aldo-keto reductase family 1, member B10 (aldose reductase); aldo-keto reductase family 1, member B11 (aldose reductase-like); Aldose reductase like; Aldose reductase-like; aldose reductase-like 1; aldose reductase-like peptide; Aldose reductase-related protein; ALDRLn; ARL 1; ARL-1; ARL1; ARP; hARP; HSI; SI reductase; Small intestine reductase
Gene Aliases: 2310005E10Rik; AKR1B10; AKR1B11; AKR1B12; Akr1b16; ALDRLn; ARL-1; ARL1; HIS; HSI
UniProt ID: (Human) O60218