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Proteintech
AKTIP Polyclonal Antibody
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Product Details
14860-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
AKTIP Fusion Protein Ag6662 (1-292 aa encoded by BC001134)
Conjugate
Form
Liquid
Concentration
0.21 mg/mL
Amount
31.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MNPFWSMST SSVRKRSEGE EKTLTGDVKT SPPRTAPKKQ LPSIPKNALP ITKPTSPAPA AQSTNGTHAS YGPFYLEYSL LAEFTLVVKQ KLPGVYVQPS YRSALMWFGV IFIRHGLYQD GVFKFTVYIP DNYPDGDCPR LVFDIPVFHP LVDPTSGELD VKRAFAKWRR NHNHIWQVLM YARRVFYKID TASPLNPEAA VLYEKDIQLF KSKVVDSVKV CTARLFDQPK IEDPYAISFS PWNPSVHDEA REKMLTQKKP EEQHNKSVHV AGLSWVKPGS VQPFSKEEKT VAT (1-292 aa encoded by BC001134)
Target Information
Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Regulates apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the AKT1/GSK3B/NFATC1 signaling cascade.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: AKT-interacting protein; FT1; FTS; fused toes homolog; Fused toes protein; Fused toes protein homolog; unnamed protein product
Gene Aliases: AKTIP; AL023020; Fif; Ft; FT1; FTS
UniProt ID: (Human) Q9H8T0, (Rat) Q5FVH4, (Mouse) Q64362
Entrez Gene ID: (Human) 64400, (Rat) 291906, (Mouse) 14339
positive regulation of protein phosphorylation
postreplication repair
apoptotic process
endosome organization
lysosome organization
endosome to lysosome transport
protein transport
positive regulation of protein binding
early endosome to late endosome transport
protein K63-linked ubiquitination
protein localization to perinuclear region of cytoplasm
protein ubiquitination
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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