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Product Details
PA5-59734
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human AKTIP. Recombinant protein control fragment (Product #RP-98740).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2637826
Product Specific Information
Immunogen sequence: WFGVIFIRHG LYQDGVFKFT VYIPDNYPDG DCPRLVFDIP VFHPLVDPTS GELDVKRAFA KWRRNHNHIW QVLMYARRVF YKIDTASP
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.
Target Information
Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Regulates apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the AKT1/GSK3B/NFATC1 signaling cascade.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AKT-interacting protein; Ft1; fused toes homolog; Fused toes protein homolog
Gene Aliases: AKTIP; FT1; FTS
UniProt ID: (Human) Q9H8T0
Entrez Gene ID: (Human) 64400
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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