Peptide sequence: YGPVPESHAC ALAWLDTQDR CLGHYVNGKW LKPEHRNSVP CQDPITGENL
Sequence homology: Cow: 86%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 92%; Rabbit: 79%; Rat: 100%
This gene encodes a member of the aldehyde dehydrogenase superfamily. The family members act on aldehyde substrates and use nicotinamide adenine dinucleotide phosphate (NADP) as a cofactor. This gene is conserved in chimpanzee, dog, cow, mouse, rat, and zebrafish. The protein encoded by this gene interacts with maspardin, a protein that when truncated is responsible for Mast syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: aldehyde dehydrogenase 16 family member A1; aldehyde dehydrogenase 16 family, member A1; aldehyde dehydrogenase 16A1; Aldehyde dehydrogenase family 16 member A1
Gene Aliases: 2410004H02Rik; AI452234; ALDH16A1; BOS_17636; mFLJ00209