This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Recommended positive controls: IMR32, mouse liver, mouse testis, rat testis.
Predicted reactivity: Mouse (97%), Rat (98%), Xenopus laevis (91%), Dog (99%), Chicken (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Three transcript variants encoding distinct isoforms have been identified for this gene.
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Protein Aliases: AL1A2; alcohol dehydrogenase family 1, subfamily A2; alcohol dehydrogenase family 1, subfamily A7; aldehyde dehydrogenase 1 family, member A2; aldehyde dehydrogenase 1A2; Aldehyde dehydrogenase family 1 member A2; aldehyde dehydrogenase family 1, subfamily A2; RALDH 2; RALDH(II); ralDH2; Retinal dehydrogenase 2; retinal dehydrogenase, type II; retinaldehyde dehydrogenase 2; Retinaldehyde-specific dehydrogenase type 2
Gene Aliases: ALDH1A2; Aldh1a7; AV116159; RALDH(II); Raldh-2; Raldh1; RALDH2; RALDH2-T