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ALDH1B1 Antibody (PA5-28554) in ICC/IF
ALDH1B1 Polyclonal Antibody detects ALDH1B1 protein at mitochondria by immunofluorescent analysis. Sample: HeLa cells were fixed in ice-cold MeOH for 5 min. Green: ALDH1B1 protein stained by ALDH1B1 Polyclonal Antibody (Product # PA5-28554) diluted at 1:500. Blue: Hoechst 33342 staining.
Product Details
PA5-28554
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 226 and 517 of Human ALDH1B1
Conjugate
Unconjugated
Form
Liquid
Concentration
0.87 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2546030
Product Specific Information
Recommended positive controls: A431.
Predicted reactivity: Mouse (94%), Rat (94%), Chimpanzee (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Aldehyde dehydrogenases (ALDHs) mediate NADP+-dependent oxidation of aldehydes into acids during detoxification of alcohol-derived acetaldehyde, lipid peroxidation and metabolism of corticosteroids, biogenic amines and neurotransmitters. Alcohol drinking habits and cardiovascular disease risk factors may be associated with ALDH gene variants. ALDH1B1 (Aldehyde dehydrogenase family 1 member B1), also known as ALDH5 or ALDHX (Aldehyde dehydrogenase X, mitochondrial), is a 517 amino acid mitochondrial protein that is expressed in the liver, testis and to a lesser extent in brain. ALDH1B1 belongs to the aldehyde dehydrogenase family and may play a major role in ethanol detoxification.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: acetaldehyde dehydrogenase 5; aldehyde dehydrogenase 1 family, member B1; Aldehyde dehydrogenase 5; Aldehyde dehydrogenase family 1 member B1; Aldehyde dehydrogenase X, mitochondrial; ALDH class 2; MGC2230
Gene Aliases: 2700007F14Rik; ALDH1B1; ALDH5; ALDHX
UniProt ID: (Human) P30837, (Mouse) Q9CZS1
Entrez Gene ID: (Human) 219, (Mouse) 72535
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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