Positive Control: mouse liver, mouse brain, rat brain, rat kidney
Predicted Reactivity: Human (100%), Rhesus Monkey (95%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
ALDH1L1 catalyzes the conversion of 10-formyltetrahydrofolate, NADP, and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family and is responsible for formate oxidation in vivo. Deficiencies in this gene can result in an accumulation of formate and subsequent methanol poisoning.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 10-formyltetrahydrofolate dehydrogenase; 10-FTHFDH; 10fTHF; 10FTHFDH; aldehyde dehydrogenase 1 family member L1; aldehyde dehydrogenase 1 family, member L1; Aldehyde dehydrogenase family 1 member L1; Cytosolic 10-formyltetrahydrofolate dehydrogenase; FBP-CI; formyltetrahydrofolate dehydrogenase; FTHFD; MER57B-ALDH1L1
Gene Aliases: 10-fTHF; 10-FTHFDH; 1810048F20Rik; ALDH1L1; FDH; FTHFD; Neut2