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Invitrogen
ALDH1L1 Polyclonal Antibody
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FIGURE: 1 / 6
ALDH1L1 Antibody (PA5-78622) in WB
Western blot was performed using Anti-ALDHL1 Polyclonal Antibody (Product # PA5-78622) and a 100, 52 kDa band corresponding to ALDHL1 was observed in the tissues tested except Mouse Spleen and Rat Spleen. Whole cell extracts (30 µg lysate) of Mouse Liver (Lane 1), Rat Liver (Lane 2), Mouse Kidney (Lane 3), Mouse Spleen (Lane 4) and Rat Spleen(Lane 5) were electrophoresed using NuPAGE™ 4-12% Bis-Tris Protein Gel (Product # NP0322BOX). Resolved proteins were then transferred onto a nitrocellulose membrane (Product # IB23001) by iBlot® 2 Dry ... View More
Product Details
PA5-78622
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human ALDH1L1. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.97 mg/mL
Amount
97 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Control: mouse liver, mouse brain, rat brain, rat kidney
Predicted Reactivity: Human (100%), Rhesus Monkey (95%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
ALDH1L1 catalyzes the conversion of 10-formyltetrahydrofolate, NADP, and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family and is responsible for formate oxidation in vivo. Deficiencies in this gene can result in an accumulation of formate and subsequent methanol poisoning.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 10-formyltetrahydrofolate dehydrogenase; 10-FTHFDH; 10fTHF; 10FTHFDH; Aldehyde dehydrogenase family 1 member L1; Cytosolic 10-formyltetrahydrofolate dehydrogenase; DKFZp781N0997; FBP-CI; formyltetrahydrofolate dehydrogenase; MER57B-ALDH1L1; unnamed protein product
Gene Aliases: 10-fTHF; 10-FTHFDH; 1810048F20Rik; ALDH1L1; FDH; FTHFD; Neut2
UniProt ID: (Human) O75891, (Rat) P28037, (Mouse) Q8R0Y6
Entrez Gene ID: (Human) 10840, (Rat) 64392, (Mouse) 107747
catalytic activity
aldehyde dehydrogenase (NAD) activity
protein binding
formyltetrahydrofolate dehydrogenase activity
oxidoreductase activity
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
aldehyde dehydrogenase [NAD(P)+] activity
methyltransferase activity
hydroxymethyl-, formyl- and related transferase activity
protein complex binding
aldehyde dehydrogenase (NADP+) activity
dehydrogenase
oxidoreductase
metabolite interconversion enzyme
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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