|Immunohistochemistry (Paraffin) (IHC (P))||3-5 ug/ml|
|Western Blot (WB)||0.01-0.03 ug/ml|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (RYPPSPAKMTQH) corresponding to the C-terminus amino acids of ALDH3A1|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: alcohol dehydrogenase family 3, subfamily A1; Aldehyde dehydrogenase 3; aldehyde dehydrogenase 3 family, member A1; aldehyde dehydrogenase 3 family, memberA1; aldehyde dehydrogenase 3, stomach cytosolic (class 3); aldehyde dehydrogenase 3A1; Aldehyde dehydrogenase 4; Aldehyde dehydrogenase family 3 member A1; aldehyde dehydrogenase isozyme 3; aldehyde dehydrogenase type III; Aldehyde dehydrogenase, dimeric NADP-preferring; ALDH3; ALDH3A1; ALDHIII; Dioxin-inducible aldehyde dehydrogenase 3; MGC10406; stomach aldehyde dehydrogenase
Gene Aliases: Ahd-4; Ahd4; Aldh; ALDH3; ALDH3A1; Aldh4; ALDHIII
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.