Immunogen sequence: LHKNEWNAYY EEVVYVLEEI EYMIQKLPEW AADEPVEKTP QTQQDELYIH SEPL
Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. ALDH3A1 forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. The enzyme is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea.
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Protein Aliases: Aldehyde dehydrogenase 3; aldehyde dehydrogenase 3 family, member A1; Aldehyde dehydrogenase family 3 member A1; aldehyde dehydrogenase isozyme 3; aldehyde dehydrogenase type III; Aldehyde dehydrogenase, dimeric NADP-preferring; ALDH3; ALDHIII; stomach aldehyde dehydrogenase
Gene Aliases: ALDH3; ALDH3A1; ALDHIII
UniProt ID: (Human) P30838
Entrez Gene ID: (Human) 218