ALDH3B2 (aldehyde dehydrogenase 3 family, member B2), also known as ALDH8, is a 385 amino acid protein that belongs to the ALDH family and is involved in the pathway of alcohol metabolism. Expressed in salivary gland tissue, ALDH3B2 functions to catalyze the NADP+-dependent conversion of an aldehyde into an acid. The gene encoding ALDH3B2 maps to human chromosome 11, which houses over 1, 400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
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Protein Aliases: acetaldehyde dehydrogenase 8; aldehyde dehydrogenase 3 family, member B2; Aldehyde dehydrogenase 8; Aldehyde dehydrogenase family 3 member B2
Gene Aliases: AI848594; Aldh3b2; ALDH8; C130048D07Rik
UniProt ID: (Mouse) E9Q3E1