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Invitrogen
ALDH3B2 Polyclonal Antibody
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FIGURE: 1 / 2
ALDH3B2 Antibody (PA5-37122) in IHC (P)
Immunohistochemistry analysis of ALDH3B2 in paraffin-embedded human liver carcinoma tissue (cytoplasm and membrane staining) and negative control (right, with PBS only). Samples were incubated with ALDH3B2 polyclonal antibody (Product # PA5-37122) at a dilution of 1:50, followed by goat Anti-Rabbit IgG-biotin and avidin peroxidase.
Product Details
PA5-37122
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to residues in human ALDH3B2
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody detects endogenous protein at a molecular weight of 43 kDa.
Purity is >95% by SDS-PAGE.
Target Information
ALDH3B2 (aldehyde dehydrogenase 3 family, member B2), also known as ALDH8, is a 385 amino acid protein that belongs to the ALDH family and is involved in the pathway of alcohol metabolism. Expressed in salivary gland tissue, ALDH3B2 functions to catalyze the NADP+-dependent conversion of an aldehyde into an acid. The gene encoding ALDH3B2 maps to human chromosome 11, which houses over 1, 400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: acetaldehyde dehydrogenase 8; aldehyde dehydrogenase 3 family, member B2; Aldehyde dehydrogenase 8; Aldehyde dehydrogenase family 3 member B2; ALDH3B2; Long-chain fatty aldehyde dehydrogenase; unnamed protein product
Gene Aliases: AI848594; ALDH3B2; ALDH8; C130048D07Rik
UniProt ID: (Human) P48448, (Mouse) E9Q3E1
Entrez Gene ID: (Human) 222, (Mouse) 621603, (Rat) 688800
3-chloroallyl aldehyde dehydrogenase activity
aldehyde dehydrogenase (NAD) activity
aldehyde dehydrogenase [NAD(P)+] activity
protein binding
oxidoreductase activity
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
long-chain-aldehyde dehydrogenase activity
medium-chain-aldehyde dehydrogenase activity
molecular_function
dehydrogenase
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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