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Proteintech
ALDH4A1 Polyclonal Antibody
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Product Details
11604-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ALDH4A1 Fusion Protein Ag2147 (246-563 aa encoded by BC023600)
Conjugate
Form
Liquid
Concentration
0.31 mg/mL
Amount
46.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: YRILREAGL PPNIIQFVPA DGPLFGDTVT SSEHLCGINF TGSVPTFKHL WKQVAQNLDR FHTFPRLAGE CGGKNFHFVH RSADVESVVS GTLRSAFEYG GQKCSACSRL YVPHSLWPQI KGRLLEEHSR IKVGDPAEDF GTFFSAVIDA KSFARIKKWL EHARSSPSLT ILAGGKCDDS VGYFVEPCIV ESKDPQEPIM KEEIFGPVLS VYVYPDDKYK ETLQLVDSTT SYGLTGAVFS QDKDVVQEAT KVLRNAAGNF YINDKSTGSI VGQQPFGGAR ASGTNDKPGG PHYILRWTSP QVIKETHKPL GDWSYAYMQ (246-563 aa encoded by BC023600)
Target Information
ALDH4A1 belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Aldehyde dehydrogenase family 4 member A1; Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; epididymis secretory sperm binding protein; L-glutamate gamma-semialdehyde dehydrogenase; mitochondrial delta-1-pyrroline 5-carboxylate dehydrogenase; P5C dehydrogenase; RP11-128M10.1; unnamed protein product
Gene Aliases: A930035F14Rik; Ahd-1; Ahd1; ALDH4; ALDH4A1; Aldh5a1; E330022C09; P5CD; P5CDH; P5cdhl; P5cdhs; Ssdh1
UniProt ID: (Human) P30038, (Mouse) Q8CHT0
Entrez Gene ID: (Human) 8659, (Rat) 641316, (Mouse) 212647
1-pyrroline-5-carboxylate dehydrogenase activity
aldehyde dehydrogenase (NAD) activity
protein binding
electron carrier activity
oxidoreductase activity
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
identical protein binding
structural molecule activity
dehydrogenase
oxidoreductase
metabolite interconversion enzyme
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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