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Proteintech
ALDH7A1 Polyclonal Antibody
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Product Details
10368-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ALDH7A1 Fusion Protein Ag0383 (196-398 aa encoded by BC002515)
Conjugate
Form
Liquid
Concentration
0.15 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: SLISVAVTK IIAKVLEDNK LPGAICSLTC GGADIGTAMA KDERVNLLSF TGSTQVGKQV GLMVQERFGR SLLELGGNNA IIAFEDADLS LVVPSALFAA VGTAGQRCTT ARRLFIHESI HDEVVNRLKK AYAQIRVGNP WDPNVLYGPL HTKQAVSMFL GAVEEAKKEG GTVVYGGKVM DRPGNYVEPT IVTGLGHDAS IAHT (196-398 aa encoded by B C002515)
Target Information
The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular member has homology to a previously described protein from the green garden pea, the 26g pea turgor protein. It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix. Recent reports show that this protein is found both in the cytosol and the mitochondria, and the two forms likely arise from the use of alternative translation initiation sites. An additional variant encoding a different isoform has also been found for this gene. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have also been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 26g turgor protein homolog; aldehyde dehydrogenase 7 family, member A1; Aldehyde dehydrogenase family 7 member A1; aldehyde dehydrogenase family 7, member A1; Alpha-AASA dehydrogenase; Alpha-aminoadipic semialdehyde dehydrogenase; Antiquitin 1; Antiquitin-1; Antiquitin1; Betaine aldehyde dehydrogenase; Delta1-piperideine-6-carboxylate dehydrogenase; delta1-piperideine-6-carboxylate dehydrogenease; P6c dehydrogenase
Gene Aliases: Ald7a1; ALDH7A1; antiquitin; ATQ1; D18Wsu181e; EPD; PDE
UniProt ID: (Human) P49419, (Rat) Q64057, (Mouse) Q9DBF1
Entrez Gene ID: (Human) 501, (Rat) 291450, (Mouse) 110695
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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