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Invitrogen
ALDH8A1 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Product Details
PA5-55298
| Applications | Tested Dilution | Publications |
|---|---|---|
Immunohistochemistry (IHC) |
1:200-1:500 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant protein corresponding to Human ALDH8A1 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.05 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.2, with 40% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2637846 |
Product Specific Information
Immunogen sequence: LPCSSYIDSY DPSTGEVYCR VPNSGKDEIE AAVKAAREAF PSWSSRSPQE RSRVLNQVAD LLEQS
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 85%.
Target Information
This protein belongs to the aldehyde dehydrogenases family of proteins. It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal. Two transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2-aminomuconic semialdehyde dehydrogenase; Aldehyde dehydrogenase 12; aldehyde dehydrogenase 8 family, member A1; Aldehyde dehydrogenase family 8 member A1; aldehyde dehydrogenase family protein
Gene Aliases: ALDH12; ALDH8A1; DJ352A20.2
UniProt ID: (Human) Q9H2A2
Entrez Gene ID: (Human) 64577
Molecular Function:
dehydrogenase
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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