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ALDH9A1 belongs to the aldehyde dehydrogenase family of proteins. The protein has a high activity for oxidation of gamma-aminobutyraldehyde and other amino aldehydes. The enzyme catalyzes the dehydrogenation of gamma-aminobutyraldehyde to gamma-aminobutyric acid (GABA). This isozyme is a tetramer of identical 54-kD subunits.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 4-trimethylaminobutyraldehyde dehydrogenase; 4-trimethylaminobutyraldehyde dehydrogenase, N-terminally processed; aldehyde dehydrogenase (NAD+); aldehyde dehydrogenase 9 family, member A1; Aldehyde dehydrogenase E3 isozyme; Aldehyde dehydrogenase family 9 member A1; Gamma-aminobutyraldehyde dehydrogenase; R-aminobutyraldehyde dehydrogenase; TMABA-DH
Gene Aliases: ALDH4; ALDH7; ALDH9; ALDH9A1; E3; TMABADH
UniProt ID: (Human) P49189
Entrez Gene ID: (Human) 223
Molecular Function:
dehydrogenase
oxidoreductase
metabolite interconversion enzyme
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