Positive Samples: HeLa, 22Rv1, NCI-H460, Mouse liver, Mouse kidney, Rat liver, Rat kidney; Cellular Location: Cytoplasm
Early endosomal protein that functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. Plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex. Possibly associated with TGF-beta receptor internalization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 4-trimethylaminobutyraldehyde dehydrogenase; 4-trimethylaminobutyraldehyde dehydrogenase, N-terminally processed; aldehyde dehydrogenase (NAD+); aldehyde dehydrogenase 9 family, member A1; aldehyde dehydrogenase 9A1; Aldehyde dehydrogenase E3 isozyme; Aldehyde dehydrogenase family 9 member A1; aldehyde dehydrogenase family 9, subfamily A1; Gamma-aminobutyraldehyde dehydrogenase; gamma-trimethylaminobutyraldehyde dehydrogenase; R-aminobutyraldehyde dehydrogenase; TMABADH
Gene Aliases: AA139417; Abaldh; ALDH4; ALDH7; ALDH9; ALDH9A1; E3; ESTM40; TMABA-DH; TMABADH