Protein kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical conformation (PubMed:10021370). Regulates cardiac development and cardiomyocyte differentiation by negatively regulating Wnt/beta-catenin signaling (PubMed:29888752). [UniProt]
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Protein Aliases: alpha-kinase 2; Alpha-protein kinase 2; alpk2; heart alpha-kinase; Heart alpha-protein kinase; RNF18
Gene Aliases: ALPK2; Gm549; HAK; RGD1564431
Molecular Function: non-receptor serine/threonine protein kinase