Immunogen sequence: EEAPFTGTTT ISFSNLGGVH KENASLAQHS EVKPCTCGPQ HEEKQDRDGN IPDNFREDLK YEQSISEAND ETMSPGVFSR HLPKDARAD
Highest antigen sequence identity to the following orthologs: Mouse - 34%, Rat - 35%.
Protein kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical conformation (PubMed:10021370). Regulates cardiac development and cardiomyocyte differentiation by negatively regulating Wnt/beta-catenin signaling (PubMed:29888752). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: alpha-kinase 2; Alpha-protein kinase 2; heart alpha-kinase; Heart alpha-protein kinase; RNF18
Gene Aliases: ALPK2; HAK
UniProt ID: (Human) Q86TB3
Entrez Gene ID: (Human) 115701