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Proteintech
ALR Polyclonal Antibody
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Product Details
11293-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ALR Fusion Protein Ag1840 (1-125 aa encoded by BC028348)
Conjugate
Form
Liquid
Concentration
0.36 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MRTQQKRDT KFREDCPPDR EELGRHSWAV LHTLAAYYPD LPTPEQQQDM AQFIHLFSKF YPCEECAEDL RKRLCRNHPD TRTRACFTQW LCHLHNEVNR KLGKPDFDCS KVDERWRDGW KDGSCD (1-125 aa encoded by B C028348)
Target Information
Isoform 1: FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re- oxidized by donating electrons to cytochrome c or molecular oxygen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Augmenter of liver regeneration; ERV1 homolog; erv1-like growth factor; FAD-linked sulfhydryl oxidase ALR; growth factor, erv1 homolog; growth factor, erv1-like (augmenter of liver regeneration); hepatic regenerative stimulation substance; Hepatopoietin; hepatopoietin protein; hERV1
Gene Aliases: ALR; ERV1; GFER; HERV1; HPO; HPO1; HPO2; HSS; MNCb-0663
UniProt ID: (Human) P55789, (Rat) Q63042, (Mouse) P56213
Entrez Gene ID: (Human) 2671, (Rat) 27100, (Mouse) 11692
oxidation-reduction process
response to lipopolysaccharide
negative regulation of apoptotic process
negative regulation of natural killer cell mediated cytotoxicity
cellular response to lipopolysaccharide
cellular response to tumor necrosis factor
cellular response to actinomycin D
cellular response to toxic substance
liver regeneration
negative regulation of oxidative stress-induced neuron death
positive regulation of DNA biosynthetic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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