Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:1,000 | View 9 publications 9 publications |
Immunohistochemistry (IHC) |
- | View 1 publication 1 publication |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:20-1:200 | - |
Immunocytochemistry (ICC/IF) |
- | View 4 publications 4 publications |
Flow Cytometry (Flow) |
Assay-dependent | View 1 publication 1 publication |
Immunoprecipitation (IP) |
0.5-4.0 µg | - |
Miscellaneous PubMed (Misc) |
- | View 2 publications 2 publications |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Human, Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
ALR Fusion Protein Ag1840 (1-125 aa encoded by BC028348) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.36 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.1% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: MRTQQKRDT KFREDCPPDR EELGRHSWAV LHTLAAYYPD LPTPEQQQDM AQFIHLFSKF YPCEECAEDL RKRLCRNHPD TRTRACFTQW LCHLHNEVNR KLGKPDFDCS KVDERWRDGW KDGSCD (1-125 aa encoded by B C028348)
Isoform 1: FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re- oxidized by donating electrons to cytochrome c or molecular oxygen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Augmenter of liver regeneration; ERV1 homolog; erv1-like growth factor; FAD-linked sulfhydryl oxidase ALR; growth factor, erv1 homolog; growth factor, erv1-like (augmenter of liver regeneration); hepatic regenerative stimulation substance; Hepatopoietin; hepatopoietin protein; hERV1
Gene Aliases: ALR; ERV1; GFER; HERV1; HPO; HPO1; HPO2; HSS; MNCb-0663
UniProt ID: (Human) P55789, (Rat) Q63042, (Mouse) P56213
Entrez Gene ID: (Human) 2671, (Rat) 27100, (Mouse) 11692
Molecular Function:
oxidase
oxidoreductase
metabolite interconversion enzyme
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