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ALS Antibody (PA5-87723) in WB
Western blot analysis of ALS in extracts of various cell lines. Samples were incubated with ALS Polyclonal antibody (Product # PA5-87723) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
Product Details
PA5-87723
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 396-605 of human IGFALS (NP_0049611)
Conjugate
Form
Liquid
Concentration
1.89 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2804368
Product Specific Information
Immunogen sequence: SCLGRIRPHT FTGLSGLRRL FLKDNGLVGI EEQSLWGLAE LLELDLTSNQ LTHLPHRLFQ GLGKLEYLLL SRNRLAELPA DALGPLQRAF WLDVSHNRLE ALPNSLLAPL GRLRYLSLRN NSLRTFTPQP PGLERLWLEG NPWDCGCPLK ALRDFALQNP SAVPRFVQAI CEGDDCQPPA YTYNNITCAS PPEVVGLDLR DLSEAHFAPC; Positive Samples: Mouse lung, Rat liver; Cellular Location: extracellular space
Target Information
The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ALS; insulin-like growth factor binding protein complex acid-labile subunit; insulin-like growth factor-binding protein complex acid labile chain; Insulin-like growth factor-binding protein complex acid labile subunit
Gene Aliases: Albs; ALS; Igfals; mKIAA4111
UniProt ID: (Rat) P35859, (Mouse) P70389
Entrez Gene ID: (Rat) 79438, (Mouse) 16005
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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