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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • ALS2CR2 Antibodies

          Invitrogen

          ALS2CR2 Polyclonal Antibody

          View all (14) ALS2CR2 antibodies

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          Cite ALS2CR2 Polyclonal Antibody

          • Antibody Testing Data (3)
          ALS2CR2 Antibody in Immunocytochemistry (ICC/IF)
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          ALS2CR2 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          ALS2CR2 Antibody (PA5-28635) in ICC/IF

          ALS2CR2 Polyclonal Antibody detects ALS2CR2 protein at Golgi apparatus by immunofluorescent analysis. Sample: HepG2 cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: ALS2CR2 protein stained by ALS2CR2 Polyclonal Antibody (Product # PA5-28635) diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 µm. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          ALS2CR2 Antibody in Immunocytochemistry (ICC/IF)
          ALS2CR2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          ALS2CR2 Antibody in Western Blot (WB)

          Product Details

          PA5-28635

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:3,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:100-1:1,000
          -

          Immunocytochemistry (ICC/IF)

          1:100-1:1,000
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ALS2CR2. The exact sequence is proprietary.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1.03 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          0.1M tris glycine, pH 7, with 10% glycerol

          Contains

          0.01% thimerosal

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2546111

          Product Specific Information

          Recommended positive controls: HeLa.

          Predicted reactivity: Rhesus Monkey (100%).

          Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

          Target Information

          This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene.

          ⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 2; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein; CALS-21; ILP-interacting protein; ILP-interacting protein ILPIPA; MGC102916; Pseudokinase ALS2CR2; STE20-related kinase adapter protein beta; STRAD beta

          View more View less

          Gene Aliases: ALS2CR2; CALS-21; ILPIP; ILPIPA; PAPK; PRO1038; STRADB

          View more View less

          UniProt ID: (Human) Q9C0K7

          View more View less

          Entrez Gene ID: (Human) 55437

          View more View less

          Function(s)
          protein kinase activity protein binding ATP binding non-receptor serine/threonine protein kinase
          Process(es)
          cell morphogenesis protein phosphorylation protein export from nucleus cell cycle arrest activation of protein kinase activity negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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