Positive Samples: HeLa, A-549, B cells, SKOV3, HL-60, Mouse testis, Mouse spleen, Mouse thymus, Rat brain; Cellular Location: Cytoplasm, Nucleus, Nucleus speckle
The protein encoded by this gene is a heat stable, nuclear protein and functions as a molecular chaperone. It is thought to regulate dimerization, DNA binding, and transcriptional activity of basic region-leucine zipper (bZIP) proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Ally of AML-1 and LEF-1; Aly/REF export factor; bZIP enhancing factor; bZIP-enhancing factor BEF; REF1-I; RNA and export factor binding protein 1; RNA and export factor-binding protein 1; Tcra enhancer-binding factor interacting protein 1; THO complex 4; THO complex subunit 4; Tho4; Transcriptional coactivator Aly/REF
Gene Aliases: ALY; ALY/REF; ALYREF; BEF; REF; REF1; Refbp1; THOC4