Sequence of this protein is as follows: MRSLGALLLL LSACLAVSAG PVPTPPDNIQ VQENFNISRI YGKWYNLAIG STCPWLKKIM DRMTVSTLVL GEGATEAEIS MTSTRWRKGV CEETSGAYEK TDTDGKFLYH KSKWNITMES YVVHTNYDEY AIFLTKKFSR HHGPTITAKL YGRAPQLRET LLQDFRVVAQ GVGIPEDSIF TMADRGECVP GEQEPEPILI PRVRRAVLPQ EEEGSGGGQL VTEVTKKEDS CQLGYSAGPC MGMTSRYFYN GTSMACETFQ YGGCMGNGNN FVTEKECLQT CRTVAACNLP IVRGPCRAFI QLWAFDAVKG KCVLFPYGGC QGNGNKFYSE KECREYCGVP GDGDEELLRF SN
This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes.
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Protein Aliases: alpha 1 microglobulin/bikunin; Alpha-1 microglobulin/bikunin; Alpha-1 microglycoprotein; Alpha-1-microglobulin; AMBP protein; Bikunin; Complex-forming glycoprotein heterogeneous in charge; EDC1; growth-inhibiting protein 19; HI-30; Inter-alpha-trypsin inhibitor light chain; ITI-LC; polyprotein; Protein AMBP; Protein HC; Protein Protein HC; Trypstatin; ulinastatin; Urinary Trypsin Inhibitor; uristatin; Uronic-acid-rich protein
Gene Aliases: A1M; AI194774; AMBP; ASPI; EDC1; HCP; HI-30; HI30; IATIL; Intin4; ITI; ITIL; ITILC; UTI